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In enzymology, a glutamate synthase (NADPH) () is an enzyme that catalyzes the chemical reaction :L-glutamine + 2-oxoglutarate + NADPH + H+ 2 L-glutamate + NADP+ Thus, the four substrates of this enzyme are L-glutamine, 2-oxoglutarate (α-ketoglutarate), NADPH, and H+, whereas the two products are L-glutamate and NADP+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. This enzyme participates in glutamate metabolism and nitrogen metabolism. It has 5 cofactors: FAD, Iron, FMN, Sulfur, and Iron-sulfur. It occurs in bacteria and plants but not animals, and is important as it provides glutamate for the glutamine synthetase reaction. == Nomenclature == The systematic name of this enzyme class is L-glutamate:NADP+ oxidoreductase (transaminating). Other names in common use include: * glutamate (reduced nicotinamide adenine dinucleotide phosphate), synthase, * glutamate synthase (NADPH), * glutamate synthetase (NADP), * glutamine amide-2-oxoglutarate aminotransferase (oxidoreductase, NADP), * glutamine-ketoglutaric aminotransferase, * L-glutamate synthase, * L-glutamate synthetase, * L-glutamine:2-oxoglutarate aminotransferase, NADPH oxidizing, * NADPH-dependent glutamate synthase, * NADPH-glutamate synthase, and * NADPH-linked glutamate synthase. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Glutamate synthase (NADPH)」の詳細全文を読む スポンサード リンク
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